Program sounds tocsin on area drug addiction
"I do believe that 2014 will be, and can be, a turning point for Athens County," Kelly said Wednesday evening, during a presentation called "A Child Will Die," focusing on the county's drug problem. "We must petition the state for more monies… We need …
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Viagra pill for women that costs £12 and also helps you slim: Drug could be on …
The pills could cause nausea, and regulators will have to be satisfied that they are not addictive. However, it is thought that women could actually need fewer pills as their treatment progresses. Lucrative: With Viagra making up to £1.5billion a year …
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E-cigs continue to light up debate
In 2013, N.C. Attorney General Roy Cooper, along with 39 other attorney generals, submitted a letter to the U.S. Food and Drug Administration urging them to place restrictions on the advertising and ingredients of cigarettes, and to regulate the them …
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In need of support? There are many groups to be of assistance.
LOOK GOOD FEEL BETTER: Abingdon, Va., Johnston Memorial Cancer Center, 26079 Lee Hwy.; first Monday, 1 p.m.; free program for women cancer patients in active treatment; register at 276-628-8861. LUPUS FOUNDATION OF … 423-972-2974. NARCONON ARROWHEAD …
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Question by : What are the advantages and disadvantages of taking Carim 100 mg?
I am intrigued specifically what are the benefits and drawbacks of having Modafinil 200 mg? Many thanks much.

Best answer:

Answer by Colin
Carim is just another name for modafinil… the only difference in yours is 100mg is half the dose of the 200mg tablets.

In the United States, modafinil is approved by the U.S. Food and Drug Administration only for the treatment of narcolepsy, obstructive sleep apnea/hypopnea and shift work sleep disorder. In some countries, it is also approved for idiopathic hypersomnia (all forms of excessive daytime sleepiness where causes can’t be established). The usual prescribed dosage for these disorders is 200 mg once a day (less commonly, 100 to 400 mg/day in one or two doses).

For conditions other than shift work sleep disorder, modafinil is normally taken in one dose in the morning or in two doses in the morning and at midday. It is generally not recommended to take modafinil after noon: modafinil is a relatively long-acting drug with a half-life of 15 hours, and taking it during the later part of the day carries a risk of sleep disturbances

Despite extensive research into the interaction of modafinil with a large number of neurotransmitter systems, a precise mechanism or set of mechanisms of action remains unclear. It seems that modafinil, like other stimulants, increases the release of monoamines, specifically the catecholamines norepinephrine and dopamine, from the synaptic terminals. However, modafinil also elevates hypothalamic histamine levels, leading some researchers to consider Modafinil a “wakefulness promoting agent” rather than a classic amphetamine-like stimulant. Despite modafinil’s histaminergic action, it still partially shares the actions of amphetamine-class stimulants due to its effects on norepinephrine and dopamine.

A National Institute on Alcohol Abuse and Alcoholism (NIAAA) study highlighted “the need for heightened awareness for potential abuse of and dependence on modafinil in vulnerable populations” due to the drug’s effect on dopamine in the brain’s reward center. However, the synergistic actions of modafinil on both catecholaminergic and histaminergic pathways lowers abuse potential as compared to traditional stimulant drugs while maintaining the effectiveness of the drug as a wakefulness promoting agent. Studies have suggested that modafinil “has limited potential for large-scale abuse” and “does not possess an addictive potential in naive individuals.”

Modafinil was shown to be an effective treatment for attention deficit hyperactivity disorder (ADHD),however in 2006 it was found by the FDA to be unfit for use by children for that purpose. It was rejected primarily due to one suspected case of Stevens-Johnson syndrome. Cephalon’s own label for Provigil now discourages its use by children for any purpose. Other potentially effective, but unapproved targets include the treatment of depression, bipolar depression,opiate & cocaine dependence,Parkinson’s disease, schizophrenia, and disease-related fatigue, as well as fatigue that is the side effect of another medication.

In most countries, here is a paper sheet with this sort of information with the tablets. If not, you really should discuss what you need to know with the pharmacist. Although pharmacists are sometimes called chemists, they are rather different and have specific traning in the areas.

Know better? Leave your own answer in the comments!

Education Deform: School-to-Prison Pipeline
She is not afraid to say that the school resource officers in some Spokane schools are “heavy handed, pushing youths in diversion programs for carrying a pocket knife at school or smoking a little pot. … borne out, the juvenile and adult criminal …
Read more on Dissident Voice

FDA issues warning to controversial Houston cancer doctor
The Food and Drug Administration has issued a strongly worded warning letter to a controversial Houston physician, Stanislaw Burzynski, who was the subject of a USA TODAY investigation last month. Burzynski – hailed as a maverick by his fans but a …
Read more on Tucson Citizen

Epilepsy Drug Gabapentin Shows Promise In Treating Alcohol Dependence
There are just three medications used to treat alcohol dependence that have been approved by the Food and Drug Administration. One drug called disulfiram discourages drinking by making it quite unpleasant — it blocks the metabolism of alcohol and …
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NIH-funded study finds that gabapentin may treat alcohol dependence
The generic anticonvulsant medication gabapentin shows promise as an effective treatment for alcohol dependence, based on the results of a 150-patient clinical trial of the medication. Conducted by scientists supported by the National Institute on …
Read more on National Institutes of Health (press release)

Powerful painkiller without abuse protections approved using controversial …
In addition, the first hydrocodone-only opioid Zohydro, approved by an FDA panel vote of 11 to 2 in late October, is manufactured by the same company, Alkermes, that makes the popular medication Vivitrol used to treat addiction to painkillers and alcohol.
Read more on RT (blog)

Addiction Specialists Wary of New Painkiller
Addiction experts protested loudly when the Food and Drug Administration approved a powerful new opioid painkiller last month, saying that it would set off a wave of abuse much as OxyContin did when it first appeared.
Read more on New York Times

Heroin addiction often starts with painkillers, parents told
Many of today's heroin addicts start their addiction with opiate-based painkillers, prescribed by doctors following sports injuries or auto crashes, said Bartlett Police Chief Kent Williams. With DuPage County's 38 heroin overdose deaths so far this …
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Naloxone Expansion In California Will Enable Family, Friends To Save Lives At …
It was approved by the Food and Drug Administration in 1971 and is stocked in thousands of emergency rooms, ambulances and post-surgery recovery rooms across the country. But frequently, opiate users don't make it to the hospital in time. For that …
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Healthnotes: Week of Oct. 7
Join The Leukemia & Lymphoma Society's Moms In Training Team for a flexible nine-week work-out program held at 9 a.m. Saturday mornings at Jennings Beach, through Nov. 17. After the program, join your team of … Bridgeport Hospital's Ahlbin …
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Calendar of Events – HYDROFEST CANCELED
SEX AND LOVE ADDICTS ANONYMOUS 12-step recovery program, 7 p.m. Mondays at Trinity Methodist Church, 20 Route 9 North, Marmora, use side door off parking lot, not affiliated with any religions and confidentiality and privacy respected. SUICIDE …
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Kick chocolate to the curb in Choctober
Reclink is asking you to join Choctober in order to help rebuild the lives of those affected by mental illness, addiction, domestic violence and homelessness. The idea is to give up chocolate for the month, not forever. In 2012, the inaugural campaign …
Read more on The Daily Telegraph